Cancer Genomics and Systems Biology Laboratory


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We are a cancer genomics group based at the Rutgers Cancer Institute, an NCI designated Comprehensive Cancer Center in New Jersey, USA.

The ultimate goal of our research to identify fundamental principles of mutability and evolvability of cancer genomes using computational and genomic technologies. Somatic evolution in cancer contributes to the fact that no tumors are alike, and it is also a key factor that confers resistance to treatment. Therefore, understanding cancer evolution can help with better diagnosis, stratification, and treatment of cancer patients. We are members of the Rutgers CINJ Precision Medicine Initiative and Center for Systems and Computational Biology. Please see the Research and Publications pages for more details.

Members of our lab come from diverse backgrounds, with training in computer science, engineering, genomics, and molecular biology. Prospective candidates please see the Members page for available opportunities.


Apr 29, 2022 We will be funded by DoD to study early lung cancer evolution.

Apr 25, 2022 Matthew Beier joins our group!

Apr 20, 2022 Bassel's Neighbor-seq is accepted in Nucleic Acids Res.

Apr 5, 2022 Xiaoju's work on fusion genes in MSI CRC is accepted in JCO Precision Oncology.

Oct 01, 2021 Dr. Suman Ghosal joins CINJ to work with Dr. Christian Hienrich and our group.

Sep 22, 2021 Dr. Vijay Singh joins our group! Welcome Vijay!

Sep 21, 2021 Subho gives a talk at the NCI ITCR Annual meeting and takes part in the panel discussion.

Apr 21, 2021 Bassel and Subho's provisional patents are filed with the U.S. Patent and Trademark Office.

Dec 16, 2020 Subho gives an invited talk at Merck Inc.

Sep 17, 2020 Subho gives an invited talk at University of Rochester Wilmont Cancer Institute.

Oct 20, 2020 Lucian's paper is accepted in Nature Communications!

Oct 9, 2019 Bassel has received ACTS fellowship - Congratulations!

Sep 17, 2019 Anchal's paper on non-genetic heterogeneity and tumor evolutionary dynamics is accepted in Cell Reports!

Aug 1, 2019 Bassel Ghaddar and Dr. Antara Biswas join our group. Welcome!

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Aug 1, 2019 Our lab is one of the winners of the 10X Genomics Single Cell Genomes Scientific Challenge!

April 1, 2019 We thank NIH for supporting our research.

Sep 6, 2018 Yizhou's paper on DYNLL1 is accepted in Nature!

Aug 10, 2018 Abdul's work is scheduled for the next issue of Nat Genetics !

Aug 9, 2018 Neil's work is accepted in Trends in Cancer.

Mar 28, 2018 Anchal's paper on regulatory alterations in Pan-cancer genomes is in press. Congrats!

Mar 26, 2018 Vinod Singh joins the group. Welcome Vinod!

Dec 16, 2017 Subho giving a talk at the Institute for Quantitative Biomedicine.

Sep 13, 2017 Subho giving a talk at the Innovative Statistics and Machine Learning for Precision Medicine conference at Univ. Minnesota.

July 30, 2017 Subho giving a talk at the RECOMB-CCB meeting.

June 23, 2017 Kyle's paper is accepted in Nature Str Mol Biol. ! Very well done!