Cancer Genomics and Systems Biology Laboratory

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Welcome!

Our lab is interested in studying cancer evolution through the use of genomics, computational and experimental approaches. We develop methodologies and resources to track cancer evolution in patients, and collaborate with our clinical colleagues for early detection, stratification, and clinical management of cancer patients.  Please see the Research and Publications pages for more details.

Our lab is affiliated to the Center for Systems and Computational Biology, Center of Excellence in Cancer Immunology and Metabolism, and involved in the Rutgers Precision Medicine Initiative in cancer

Members of our lab come from diverse backgrounds, with training in computer science, engineering, genomics, and molecular biology. Prospective PhD students from the Molecular Biosciences, Quantitative Biomedicine, and Biotechnology graduate programs at Rutgers are encouraged to apply. Prospective postdoctoral candidates please see the Members page for available opportunities.  

News

Jan 9, 2024 Our lab's research in cancer genomics and R35 grant were highlighted in the Dean's letter at Rutgers.

Dec 13, 2023 Xiaoju and Subho's News&Views on domain-level mutational signatures is in press in Nature Cancer!

Dec 8, 2023 Bassel's new method Census on accurate, automated, deep, fast, and hierarchical scRNA-seq cell-type annotation is published in Bioinformatics!

Dec 4, 2023 Antara's paper on dynamic non-genetic heterogeneity in bladder cancer is accepted in Communications Biology! 

Oct 10, 2023 Bassel's new method Sahmi for denoising sparse microbial signals from single-cell sequencing of mammalian host tissues is published in Nature Computational Science. Research highlights in Rutgers Today

Sep 18, 2023 Our lab gets the NIH R35 grant to continue working on somatic variations and cancer evolution

June 10, 2023 Subho joins NIH GVE study section as a standing member

Dec 10, 2022 Subho is invited to join the Academy of Mentors for NJ-Alliance for Clinical and Translational Sciences. 

Oct 10, 2022 Bassel's paper on tumor-microbiome-immune crosstalk in pancreatic cancer is published in Cancer Cell. Research highlights in Cancer Cell and Science

Sep 14, 2022 Bassel's talk on Neighbor-seq at ITCR Annual meeting received award in the best presentation category.

Sep 02, 2022 Antara and Bassel's paper on spatial heterogeneity in cancer is published in Computational and Systems Oncology.

Aug 01, 2022 We thank DoD for funding our research on lung cancer. 

June 28, 2022 Congratulations Antara for getting the NJCCR Fellowship! 

June 16, 2022 Bassel's applications on host-microbiome signatures in cancer highlighted by Rutgers Innovation.

May 25, 2022 Antara and Xiaoju both win prestigious Gala awards for stellar talks at the 2022 Annual retreat. Proud of the lab! 

May 18, 2022 Xiaoju's paper is out. There is a nice News&Views about it by Krista Didzbalis.

May 16, 2022 Bassel's Neighbor-seq paper is out in Nucleic Acids Res. It is already picked up by GenomeWeb and other platforms!  

Apr 25, 2022 Matthew Beier joins our group

Apr 20, 2022 Bassel's Neighbor-seq is accepted in Nucleic Acids Res. 

Apr 05, 2022 Xiaoju's work on fusion genes in MSI CRC is accepted in JCO Precision Oncology. 

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Oct 01, 2021 Dr. Suman Ghosal joins CINJ to work with Dr. Christian Hienrich and our group.

Sep 22, 2021 Dr. Vijay Singh joins our group! Welcome Vijay!

Sep 21, 2021 Subho gives a talk at the NCI ITCR Annual meeting and takes part in the panel discussion.

Apr 21, 2021 Bassel and Subho's provisional patents are filed with the U.S. Patent and Trademark Office.

Dec 16, 2020 Subho gives an invited talk at Merck Inc.

Sep 17, 2020 Subho gives an invited talk at University of Rochester Wilmont Cancer Institute.

Oct 20, 2020 Lucian's paper is accepted in Nature Communications!

Oct 09, 2019 Bassel has received ACTS fellowship - Congratulations!

Sep 17, 2019 Anchal's paper on non-genetic heterogeneity and tumor evolutionary dynamics is accepted in Cell Reports!

Aug 01, 2019 Bassel Ghaddar and Dr. Antara Biswas join our group. Welcome!

Aug 01, 2019 Our lab is one of the winners of the 10X Genomics Single Cell Genomes Scientific Challenge!

April 1, 2019 We thank NIH for supporting our research. 

Sep 06, 2018 Yizhou's paper on DYNLL1 is accepted in Nature!

Aug 10, 2018 Abdul's work is scheduled for the next issue of Nat Genetics !

Aug 09, 2018 Neil's work is accepted in Trends in Cancer.

Mar 28, 2018 Anchal's paper on regulatory alterations in Pan-cancer genomes is in press. Congrats!

Mar 26, 2018 Vinod Singh joins the group. Welcome Vinod! 

Dec 16, 2017 Subho giving a talk at the Institute for Quantitative Biomedicine.

Sep 13, 2017 Subho giving a talk at the Innovative Statistics and Machine Learning for Precision Medicine conference at Univ. Minnesota.

July 30, 2017 Subho giving a talk at the RECOMB-CCB meeting. 

June 23, 2017 Kyle's paper is accepted in Nature Str Mol Biol. ! Very well done!